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KMID : 1041220040460010028
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Journal of Sericultural and Entomological Science
2004 Volume.46 No. 1 p.28 ~ p.31
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Infrared Spectroscopy and Differential Scanning Calorimetry of Silk Fibroin/Hyaluronic Acid Blend Film
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Kwon Hae-Yong
Park Young-Hwan
Lee Jang-Hern
Yeo Joo-Hong
Lee Kwang-Gill
Lee Yong-Woo
Han Sang-Mi
Woo Soon-Ok
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Abstract
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Bombyx mori silk fibroin/hyaluronic acid blend films were prepared by mixing aqueous solution of B. mori silk fibroin and hyaluronic acid. According to the FTIR spectra, no interaction between silk fibroin and hyaluronic acid was found. The conformation of silk fibroin in blend films was changed from random coil to $\beta$-sheet structure by treatment of EDC ethanol solution. Thermal degradation peak of silk fibroin and hyaluronic acid was also not altered by blending each other. The average swelling ratio of silk fibroin/hyaluronic acid blend films was 70. Therefore, silk fibroin/hyaluronic acid blend films might be one of possible wound dressing materials.
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KEYWORD
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silk fibroin, hyaluronic acid
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